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采用天然丰度钯粉（纯度≥９９．９５％）作靶料，经反应堆照射后，用ＨＮＯ＿３、ＨＣｌ氧化生成放射性氯铂酸盐；在一定酸度的条件下，以抗坏血酸作还原剂，葡萄糖和明胶作保护剂，获得氧化态为零价的钯原子胶体（游离钯离子＜０．５％）。经电子显微镜测得胶体的粒度范围为１００—４００ｎｍ。动物实验表明：￣（１０３，１０９Ｐｄ胶体高度浓集于体腔的肿瘤部位，血清除快，关节显像清晰，给大鼠注入相当于人体用量１００倍的￣（１０３，１０９）ｐｄ胶体，未观察到毒副作用。
Using natural abundance palladium powder (purity ≥ 99.95%) as target material, after irradiation by reactor, oxidizing with HNO 3 , HCl to generate radioactive chloroplatinate; under certain acidity condition, using ascorbic acid as reducing agent, glucose and Gelatin was used as a protective agent to obtain a zero-valent palladium atom colloid (free palladium ion < 0.5%). The colloidal particle size ranged from 100 to 400 nm as measured by electron microscopy. Animal experiments showed that: ̄(103,109Pd colloid was highly concentrated in the tumor cavity of the body cavity, the blood was cleared quickly, and the joint imaging was clear. The rat was injected with a ̄(103,109) pd colloid equivalent to 100 times the human body dose. To toxic side effects.