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目的探索腹盆腔晚期恶性肿瘤较好的治疗措施。方法1998年5月至2004年5月将救治的71例晚期腹盆腔恶性肿瘤患者随机分为治疗组和对照组。治疗组36例实施腹腔热化疗配合同步静脉化疗及中药扶正治疗;对照组35例采用单一的静脉化疗。观察两组患者的近期疗效、生活质量、体重、生存期的变化及毒副反应。结果治疗组临床收益率(CR+PR)、生活质量、体重、生存率均较对照组高(P<0.05)。毒副反应也较对照组低(P<0.05)。未见相关并发症的发生。结论疗效对比观察结果表明,应用腹腔热化疗配合同步静脉化疗及中药扶正治疗对晚期腹盆腔肿瘤有较好的治疗作用,比单一静脉化疗效果明显。
Objective To explore the better treatment of advanced pelvic malignant tumors. Methods From May 1998 to May 2004, 71 patients with advanced malignant tumors of the pelvic cavity were randomly divided into treatment group and control group. In the treatment group, 36 cases were treated with intraperitoneal hyperthermic chemotherapy combined with synchronous intravenous chemotherapy and Chinese herbal medicine Fuzheng. In the control group, 35 cases were treated with single intravenous chemotherapy. The curative effect, quality of life, weight, survival period and toxicity were observed in two groups of patients. Results The clinical rate of return (CR + PR), quality of life, body weight and survival rate in the treatment group were higher than those in the control group (P <0.05). Toxicity was also lower than the control group (P <0.05). No relevant complications occurred. Conclusions The comparison of curative effect shows that the application of intraperitoneal hyperthermic chemotherapy combined with intravenous chemotherapy and Chinese medicine Fuzheng treatment has a better therapeutic effect on advanced abdominal pelvic tumors and is more effective than single intravenous chemotherapy.