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目的:研究复康胶囊对化疗所致小鼠免疫功能损伤的恢复作用。方法:采用环磷酰胺制备免疫功能低下模型,测定药物对小鼠白细胞计数,免疫器官重量、脾细胞增殖反应,诱导体抗和IL-1产生的影响。结果:复康胶囊有升高小鼠白细胞,增加免疫器官重量,促进脾细胞增殖反应,诱导抗体和IL-1的产生。结论:复康胶囊能明显促进化疗损伤小鼠免疫功能的恢复。
OBJECTIVE: To study the recovery effect of Fukang Capsule on immune function damage induced by chemotherapy in mice. METHODS: Cyclophosphamide was used to prepare the immunocompromised model, and the effects of drugs on mouse leukocyte count, immune organ weight, splenocyte proliferation, and induction of body resistance and IL-1 production were determined. RESULTS: Fukang Capsules elevated white blood cells, increased the weight of immune organs, promoted splenocyte proliferation, and induced the production of antibodies and IL-1. Conclusion: Fukang capsule can significantly promote the recovery of immune function in mice with chemotherapy injury.