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目的评价医院万古霉素临床应用情况。方法调查医院2012年8月至2013年1月应用万古霉素的住院患者114例,对年龄、性别、感染类型、用药情况、病原学检查、用药疗效、不良反应/事件等进行统计分析。结果 114例患者中,应用万古霉素的有效率为64.04%,药物利用指数(DUI)为0.85,其中有病原学检测的占98.25%,与药物敏感性试验报告相符占47.37%。使用过程中存在用药不合理问题,如用法不适宜、给药途径不适宜、用量不适宜、溶剂不适宜。结论医院万古霉素临床应用基本合理,但仍存在不合理现象,临床应规范使用。
Objective To evaluate the clinical application of vancomycin in hospitals. Methods A total of 114 hospitalized patients with vancomycin in our hospital from August 2012 to January 2013 were enrolled in this study. The age, gender, type of infection, drug use, etiological examination, curative effect and adverse reactions / events were statistically analyzed. Results Among the 114 patients, the effective rate of vancomycin was 64.04%, and the drug utilization index (DUI) was 0.85. Among them, 98.25% had etiological tests, accounting for 47.37% of the reports of drug susceptibility test. There is irrational use of drugs in the course of the problem, such as the use of inappropriate, inappropriate route of administration, the amount is not appropriate, the solvent is not appropriate. Conclusion The clinical application of vancomycin in the hospital is basically reasonable, but there are still unreasonable phenomena. Clinical use should be regulated.