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在临床上,下尿路梗阻导致下尿路症状的患者越来越普遍;而在男性中,导致下尿路梗阻最为常见的疾病便是前列腺增生。临床上治疗一般予以抗毒蕈碱药物如托特罗定、索利那新等。而对于那些同时伴有膀胱过度活动症(overactive bladder,OAB)的患者而言,抗毒蕈碱药物则可能减弱膀胱逼尿肌的收缩力,从而引起尿潴留。因此,下尿路梗阻伴OAB的患者临床上究竟应如何予以药物治疗,这一直是临床医师经常面对而又困惑的问题。本文将对下尿路梗阻伴OAB的药物治疗作一综述,旨在为临床医师更好地治疗此类疾病提供参考。?
Clinically, lower urinary tract obstruction causes lower urinary tract symptoms in patients is becoming more common; in men, the most common cause of lower urinary tract obstruction is benign prostatic hyperplasia. Clinical treatment of general anti-muscarinic drugs such as tolterodine, solifenacin and so on. For those patients with overactive bladder (OAB), anti-muscarinic drugs may reduce the contractility of the detrusor of the bladder, causing urinary retention. Therefore, the lower urinary tract obstruction with OAB patients clinically how to be drug treatment, which has always been clinicians confused issues. This article will summarize the medical treatment of lower urinary tract obstruction with OAB, which aims to provide reference for clinicians to better treat such diseases. ?