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目的:评价巩膜层间填充羊膜及应用丝裂霉素治疗难治性青光眼的效果。探讨术后并发症及预防。方法:采用巩膜层间填充羊膜及丝裂霉素C治疗难治性青光眼共30例31眼。并根据不同病因及眼压控制情况,采取相应的辅助治疗。术后追踪随访1～24个月。结果:术后平均眼压15.26mmHg眼压≤21mmHg者占89.1%。术后早期并发症有浅前房,短暂性前房积血及葡萄膜炎等。远期偶有滤过泡纤维化,白内障加速发展。结论:巩膜层间填充羊膜应用丝裂霉素C经济简便,远期效果好,是治疗难治性青光眼的一种有效方法。
OBJECTIVE: To evaluate the effect of interspinous amniotic membrane filling and mitomycin treatment on refractory glaucoma. To explore postoperative complications and prevention. Methods: Thirty patients (31 eyes) with refractory glaucoma were treated with amniotic membrane interstitial sclera and mitomycin C. And according to different causes and intraocular pressure control, take the appropriate adjuvant therapy. Follow-up postoperative follow-up 1 ~ 24 months. Results: The mean IOP after operation was 15.26mmHg, with IOP ≤21mmHg accounting for 89.1%. Early postoperative complications of shallow anterior chamber, transient anterior chamber hemorrhage and uveitis. Long-term occasional bleb fibrosis, cataract accelerated development. Conclusion: The application of mitomycin C in amniotic membrane during scleral buckling is a simple and economical method with long-term effect and is an effective method for the treatment of refractory glaucoma.