肺错构瘤１９例分析山西省肿瘤医院（０３００１３）郑炳祥，李澄涛，陈允清肺错构瘤是常见的肺内良性肿瘤，发病率仅次于腺瘤，肺错构瘤占肺的良性肿瘤的８％，我院自１９６４年至１９９０年收治肺错构瘤１９例，均行手术切除，并经病理证实，现报告如下。临床资料１９例中，男１２例，女７例；年龄最小２９岁，最大６２岁。４０岁以下５例，４０～６０岁１３例，６０岁以上１例；１９例中临床上有胸闷胸痛者８例次，咳嗽者９例次，发热者４例次，血痰者３例次，呼吸困难者２例次，无症状者５例。Ｘ线检查：１９例均表现为肺内圆形成椭圆形，阴影边缘清，有的呈分叶，密度不均，球形内钙化者２例，出现液平者２例，并发肺不张者１例。病理检查：大体标本所见，均为圆形式椭圆形肿物，直径１．５～５．６ｃｍ，质硬或软硬不均，与周围肺组织界限清楚，少数有包膜，切面灰白相间，部分病例呈分叶状，有的可见软骨样组织，２例并发囊性变。镜下主要成分为软骨，其它包括平滑肌、纤维结缔组织、脂肪组织及淋巴组织。本组以软骨样错构瘤最多，１２例占６３．１５％。讨论１．肺错构瘤为正常组织异常结合的混合性的瘤样病变。其发病原因目前尚不清楚。一般认为肺错构瘤是一种先天性畸形，有人报告１例生后４ Pulmonary hamartoma 19 cases analysis Shanxi Provincial Cancer Hospital (030013) Zheng Bingxiang, Li Chengtao, Chen Yunqing Pulmonary hamartoma is a common benign lung tumor, the incidence rate is second only to adenoma, pulmonary hamartoma accounts for benign lung tumors 8 %, 19 cases of pulmonary hamartoma were treated in our hospital from 1964 to 1990. All were surgically removed and confirmed by pathology. The report is as follows. Clinical data in 19 cases, 12 males and 7 females; youngest 29 years old, maximum 62 years old. There were 5 cases under the age of 40, 13 cases between the ages of 40 and 60, and 1 case above the age of 60. In 19 cases, there were 8 cases with chest pain and chest pain, 9 cases with cough, 4 cases with fever, and 3 cases with blood stasis. There were 2 cases of dyspnea and 5 cases of asymptomatic. X-ray examination: 19 cases showed an oval shape of the lung circle, clear edge shadow, and some were lobulated, uneven density, spherical calcification in 2 cases, 2 cases of fluid level, concurrent atelectasis 1 example. Pathological examination: Gross specimens are oval-shaped round tumors, diameter 1.5 ~ 5.6cm, hard or uneven hardness, and the surrounding lung tissue clear boundaries, a small number of coated, gray and white cut surface, Some cases were lobulated, some had cartilage-like tissue, and 2 were complicated by cystic degeneration. The main component under the microscope is cartilage, and the other includes smooth muscle, fibrous connective tissue, adipose tissue, and lymphoid tissue. The group had the most chondroid hamartoma, 12 cases accounted for 63.15%. Discussion 1. Pulmonary hamartoma is a mixed tumor-like lesion that is abnormally associated with normal tissue. The cause of the disease is not yet clear. Pulmonary hamartoma is generally considered a congenital malformation, it was reported 1 case after birth 4