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目的探讨小儿手足口病流行病学特征及临床特点,总结诊断和治疗经验,提高手足口病的疗效。方法对2009年4月～2010年11月门诊及住院的680例手足口病病例进行流行病学、临床表现、治疗、转归分析。结果发病年龄集中在<5岁儿童(97.2%),<3岁患儿发病构成比最高。男女比例为1.34∶1,男性患儿明显多于女性;4～11月均有发病,高峰为4～6月。实验室诊断病例中,EV71占45.08%,CoxA16占38.34%。结论手足口病高发季节应做好疾病的防控工作,降低发病率,早期诊断和早期治疗是提高小儿手足口病疗效的关键。
Objective To investigate the epidemiological characteristics and clinical features of hand-foot-mouth disease in children, summarize the experience of diagnosis and treatment and improve the curative effect of hand-foot-mouth disease. Methods From April 2009 to November 2010, 680 cases of HFMD inpatients and inpatients were analyzed for their epidemiology, clinical manifestation, treatment and outcome. Results The age of onset was mainly in children <5 years old (97.2%). The incidence of disease was highest in children <3 years old. Male to female ratio was 1.34: 1, male patients were significantly more than women; 4 to 11 months have morbidity, the peak of 4 to 6 months. Laboratory diagnosis of cases, EV71 accounted for 45.08%, CoxA16 accounted for 38.34%. Conclusion Hand-foot-mouth disease season should be done to prevent and control diseases, reduce morbidity, early diagnosis and early treatment is the key to improve the efficacy of hand-foot-mouth disease in children.