乳腺癌是女性最常见的恶性肿瘤之一,其发病率在全球呈上升趋势,每年以0.2%~8%的幅度上升,并有年轻化趋势。肿瘤的转移和复发是导致患者死亡的主要原因。当肿瘤局限在乳腺中时,其治愈率超过90%,而当癌细胞发生远处转移后,其5年生存率低于20%。传统判断乳腺癌预后的指标有肿瘤大 Breast cancer is one of the most common malignant tumors in women. The incidence of breast cancer in the world is on an upward trend, rising by 0.2% -8% annually, and tends to be younger. Tumor metastasis and recurrence are the main causes of death in patients. When the tumor is confined to the breast, the cure rate is over 90%, whereas when the cancer cells have distant metastases, the 5-year survival rate is below 20%. The traditional indicators to determine the prognosis of breast cancer is large