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本文对月经周期规律的15例育龄妇女20个月经周期宫颈粘液及血清葡萄糖、果糖水平进行测定,同时对血清促黄体激素(LH)、促卵泡激素(FSH)、雌二醇(E2)和孕酮(P)放免测定;阴道B超、宫颈粘液Insler评分;尿LH酶联免疫测定和基础体温(BBT)测定,综合评价预测和确定排卵日。20个周期均为有排卵周期。结果:宫颈粘液葡萄糖、果糖水平均表现为卵泡期稍高,排卵前最低,排卵后逐渐升高,黄体中期达高峰;卵泡期果糖水平与E2呈负相关(r=-0.73,P<0.01);黄体期葡萄糖、果糖水平均与P呈正相关(r=0.99,P<0.01;r=0.98,P<0.01);血葡萄糖、果糖水平无周期性变化且与宫颈粘液葡萄糖、果糖水平无明显相关性(r=0.23,P>0.05)。结论:宫颈粘液葡萄糖、果糖水平变化具有明显规律性,可能与雌孕激素调节有关。
In this paper, menstrual cycle of 15 women of childbearing age 20 menstrual cycle of cervical mucus and serum glucose, fructose levels were measured at the same time on serum luteinizing hormone (LH), follicle stimulating hormone (FSH), estradiol (E2) and pregnancy (P) radioimmunoassay; vaginal B ultrasound, cervical mucus Insler score; urinary LH enzyme-linked immunosorbent assay and basal body temperature (BBT) determination, comprehensive evaluation to predict and determine the ovulation day. 20 cycles are ovulation cycle. Results: The levels of glucose and fructose in cervical mucus were slightly higher in follicular phase, lowest in ovulation group, higher in ovulation group and highest in mid-luteal phase. The follicular phase fructose level was negatively correlated with E2 (r = -0.73, P < 0.01). The levels of glucose and fructose in luteal phase were positively correlated with P (r = 0.99, P <0.01; r = 0.98, P <0.01) There was no significant correlation between cervical mucosal glucose and fructose (r = 0.23, P> 0.05). Conclusion: The changes of glucose and fructose in cervical mucus have obvious regularity, which may be related to the regulation of estrogen and progesterone.