目的:探讨结、直肠癌患者术前使用肠内营养制剂行肠道准备替代传统肠道准备方法的可行性。方法:结、直肠癌患者42例,随机分为实验组和对照组,实验组(肠内营养组,即EN组)21例,给予口服瑞素,口服肠道消炎药,静脉补液行术前肠道准备。对照组(硫酸镁组)21例,术前禁食、静脉补液,口服硫酸镁及肠道消炎药行术前肠道准备。然后分别于肠道准备前(术前第五日晨)及手术当日晨和术后第三日进行各项营养评定,比较两组的肠道清洁度,不良反应及术后并发症。结果:两组病人肠道清洁度均较好,无显著性差异(P>0.05)。实验组肠道准备期间大便次数明显少于对照组(P<0.01)。实验组病人不良反应发生率低于对照组,差异具有显著性(P<0.05)。实验组术后感染、吻合口漏发生率均低于对照组,但差异无显著性(P>0.05)。实验组患者术后肠道功能恢复时间早于对照组(P<0.01)。实验组的多项营养评定指标在肠道准备前、后明显优于对照组(P<0.05)。实验组术后的多项实验室指标均优于对照组,差异具有显著性(P<0.01)。结论:结、直肠癌患者以肠内营养制剂(瑞素)行术前肠道准备能保证良好肠道清洁度,有效改善患者术后的营养状况,减少不良反应发生,效果优于传统方法,值得在临床推广。 Objective: To investigate the feasibility of preoperative bowel preparation instead of traditional bowel preparation for enteral nutrition in patients with colorectal cancer. Methods: Twenty-two patients with colorectal cancer and colorectal cancer were randomly divided into experimental group and control group. In the experimental group (enteral nutrition group, EN group), 21 patients were given oral Reversol, oral anti-inflammatory drugs, Gut preparation. Control group (magnesium sulfate group) 21 cases, preoperative fasting, intravenous rehydration, oral magnesium sulfate and intestinal anti-inflammatory drugs preoperative intestinal preparation. The nutritional status of each group was evaluated before intestinal preparation (on the fifth morning of preoperative day) and on the day of surgery and on the third day after operation. Intestinal cleanliness, adverse reactions and postoperative complications were compared between the two groups. Results: The intestinal cleanliness was good in both groups, with no significant difference (P> 0.05). The number of stool in the experimental group during intestinal preparation was significantly less than that in the control group (P <0.01). The incidence of adverse reactions in the experimental group was lower than that in the control group, the difference was significant (P <0.05). The incidence of postoperative infection and anastomotic leakage in the experimental group was lower than that in the control group, but the difference was not significant (P> 0.05). The recovery time of intestinal function in experimental group was earlier than that in control group (P <0.01). A number of nutritional assessment indicators in the experimental group were significantly better than those in the control group before and after gut preparation (P <0.05). The experimental group after a number of laboratory indicators were better than the control group, the difference was significant (P <0.01). Conclusion: The bowel preparation of rectal cancer patients with enteral nutrition (Reisu) preoperative intestinal preparation can ensure good intestinal cleanliness, effectively improve the postoperative nutritional status and reduce adverse reactions, the effect is better than the traditional method, Worthy of clinical promotion.