肺间质纤维化为各种原因引起的慢性进行性肺间质性疾病,最终发生肺纤维化。而对红霉素及其第二代大环内酯类抗生素(以阿奇霉素为代表)研究发现其具有抗炎和免疫调节功能,有望成为临床治疗肺间质纤维化的又一途径。1资料与方法1·1临床资料:选择2001年1月至2004年1月住院的结缔 Pulmonary interstitial fibrosis is a chronic, progressive interstitial lung disease caused by a variety of causes that eventually lead to pulmonary fibrosis. Erythromycin and its second generation macrolide antibiotics (represented by azithromycin) study found that it has anti-inflammatory and immunomodulatory function, is expected to become another way of clinical treatment of pulmonary interstitial fibrosis. 1 Materials and Methods 1.1 Clinical data: select the January 2001 to January 2004 hospitalized association