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目的了解妇产科感染患者采取注射用头孢哌酮/舒巴坦治疗的安全性及有效性,并为该病的临床治疗积累经验。方法选取2010年3月-2013年3月收治的80例妇产科重度感染患者,利用随机数字表法进行分组,分别设为研究组和对照组,每组各40例;其中对照组给予头孢他啶治疗,研究组给予头孢哌酮/舒巴坦治疗,比较两组临床疗效及细菌清除率,数据采用SPSS19.0软件进行分析。结果研究组临床总有效率为90.0%,对照组为75.0%;研究组细菌清除率为82.9%,对照组为61.7%;药物不良反应发生率研究组为5.0%,对照组为7.5%,两组比较,差异有统计学意义(P<0.05)。结论妇产科感染患者采取注射用头孢哌酮/舒巴坦治疗可提高抗感染能力,且药物安全性高,取得较为满意的临床效果。
Objective To understand the safety and efficacy of cefoperazone / sulbactam in patients with obstetrics and gynecology infection and to gain experience for the clinical treatment of the disease. Methods Eighty patients with severe obstetrics and gynecology who were admitted to our hospital from March 2010 to March 2013 were selected and randomly divided into study group and control group, 40 cases in each group. The control group was given ceftazidime Treatment, the study group was given cefoperazone / sulbactam treatment, the clinical efficacy and bacterial clearance rate were compared between the two groups, the data were analyzed by SPSS19.0 software. Results The total clinical effective rate was 90.0% in the study group and 75.0% in the control group. The bacterial clearance rate was 82.9% in the study group and 61.7% in the control group. The incidence of adverse drug reactions was 5.0% in the study group and 7.5% in the control group The difference was statistically significant (P <0.05). Conclusion The treatment of patients with obstetrics and gynecology infection with cefoperazone / sulbactam injection can improve the anti-infective ability, and the drug is safe and has a satisfactory clinical effect.