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细胞间粘附分子 1(Ｉｎｔｅｒｃｅｌｌｕｌａｒａｄｈｅｓｉｏｎｍｏｌｅｃｕｌｅ ｌ,ＩＣＡＭ 1)主要在内皮细胞表达 ,作为白细胞 β2 整合素家族的配体在中性粒细胞与内皮细胞紧密结合和随后进入缺血组织中起重要作用。通过降低ＩＣＡＭ 1的表达会减轻缺血 /再灌注损伤 ,这
Intercellular adhesion molecule 1 (ICAM 1) is expressed predominantly in endothelial cells and plays an important role as a ligand for leukocyte β 2 integrin family in the tight association of neutrophils with endothelial cells and subsequent entry into ischemic tissue. This can be mitigated by reducing the expression of ICAM 1 by ischemia / reperfusion injury