长久以来,角膜被认为是免疫赦免的器官,但在新生血管化角膜及有移植排斥史的角膜中这种免疫赦免状态受到不同程度破坏,从而使这样的角膜同样成为易发生排斥的组织[1]。研究已证实血管化角膜植床能增加术后的排斥率,降低植片的存活率,并且发现新生血管的程度与术后排斥反应呈正 For a long time, the cornea was considered as an immune-forbidden organ, but this immunopapulation state was damaged to varying degrees in neovascularized corneas and in the cornea with a history of graft rejection, making such corneas similarly vulnerable to rejection [1 ]. Studies have demonstrated that vascularized corneal implantation can increase postoperative rejection and reduce the survival rate of implants, and found that the degree of neovascularization and postoperative rejection was positive