红曲的药用价值和保健功效日益引人关注,其中洛伐他汀作为红曲主要的调脂因子成为科研热点和红曲产业发展的重点。概述红曲洛伐他汀的药理作用及其生物合成途径,并结合国内外的研究进展,从优化发酵工艺和菌种改良两个层面阐述提高红曲洛伐他汀产量的途径,并对今后的研究方向进行了展望。 The medicinal value and health care efficacy of Monascus are attracting more and more attention. Lovastatin, as the main lipid-regulating factor of Monascus, has become the focus of scientific research and the development of Monascus industry. In this paper, the pharmacological action and biosynthesis pathway of rosuvastatin is summarized. Based on the research progress at home and abroad, the ways to improve the yield of rosxrestatin from the two aspects of optimization of fermentation process and strain improvement are described. The direction of the outlook.