目的：为评价叶绿素光敏剂光动力疗法（ＣＰＤ_４－ＰＤＴ）预防浸润性膀胱癌术后复发的疗效。方法：３２例浸润性膀胱癌术后患者接受叶绿素光敏剂光动力疗法，并均接受随访。结果： Ｔ_２期组与 Ｔ_３期组复发率无显著性差异（ ４２．１％和 ６９．２％， Ｐ＞ ０．０５）。单发肿瘤与多发肿瘤复发率亦无显著性差异（４４．４％和 ６４．３％，Ｐ＞０．０５）。Ｔ２期和Ｔ３期组患者无瘤生存时间（月）分别为１９．８０±１４．８０和２２．６７±１９．７２（Ｐ＞０．０５）。病理分级为Ⅰ级与Ⅱ、Ⅲ级组的复发率（０和６６．７％，）有明显差异（Ｐ＜０．００１）。结论：叶绿素光敏剂光动力疗法是一种安全有效地预防膀胱肿瘤术后复发的手段之一。 Objective: To evaluate the efficacy of chlorophyll photosensitizer photodynamic therapy (CPD_4-PDT) in preventing postoperative recurrence of invasive bladder cancer. Methods: Thirty-two patients with invasive bladder cancer received photodynamic therapy with chlorophyll photosensitizer and were followed up. Results: There was no significant difference in recurrence between T 2 and T 3 (42.1% and 69.2%, P> 0.05). Single tumor and multiple tumor recurrence rate was no significant difference (44.4% and 64.3%, P> 0.05). The tumor-free survival time in months T2 and T3 was 19.80 ± 14.80 and 22.67 ± 19.72, respectively (P> 0.05). There was a significant difference (P <0.001) between the pathological grade Ⅰ and Ⅱ, Ⅲ grade recurrence rate (0 and 66.7%, respectively). Conclusion: Chlorophyll photosensitizer photodynamic therapy is a safe and effective way to prevent postoperative recurrence of bladder cancer.