1935年 Stein 和 Leventhal 报告七例病人,双侧卵巢多囊性肿大和闭经,或者表现为月经稀少、不孕、多毛、阴蒂肥大、肥胖等一系列无排卵以及男性化症状,而且指出卵巢肿大与临床症状之间的关系,并发现巢肿大不是炎症性肿大而是由于内分泌因素引起,此后即命名为 Stein-Leventhal 综合症(S—L 综合症)。此后,即使肾上腺皮质、甲状腺、脑垂体的功能失调,卵巢也出现多囊性肿大,有关病 1935 Stein and Leventhal reported seven patients, bilateral ovarian cystic enlargement and amenorrhea, or manifested as menorrhagia, infertility, hirsutism, clitoris hypertrophy, obesity and a series of anovulatory and masculine symptoms, but also pointed out that ovarian enlargement And clinical symptoms, and found that the enlargement of the nest was not an inflammatory enlargement but was due to endocrine factors, then named Stein-Leventhal syndrome (S-L syndrome). Since then, even if the adrenal cortex, thyroid, pituitary dysfunction, polycystic ovarian also appeared swollen, the disease