论文部分内容阅读
目的观察颅脑外损伤患者采用依达拉奉治疗的临床效果。方法选取医院收治的颅脑外损伤患者60例,随机分为观察组和对照组,每组30例。对照组给予止血、脱水、神经营养药物等常规治疗,观察组在常规治疗基础上应用依达拉奉治疗。观察2组患者脑水肿变化、意识恢复相关情况。结果治疗7 d、14 d,观察组脑部水肿面积均少于对照组(P<0.05);2组患者格拉斯哥昏迷评分值(GCS评分)较治疗前均升高、急性生理与慢性健康评分值(APACHE-Ⅱ评分)较治疗前均降低(P<0.05),观察组改善程度均大于对照组(P<0.05)。结论依达拉奉用在颅脑外损伤治疗上具有消除脑水肿的效果,促进患者脑神经功能的恢复,值得临床广泛应用。
Objective To observe the clinical effect of edaravone in patients with craniocerebral injury. Methods Sixty patients with craniocerebral injury who were admitted to hospital were randomly divided into observation group and control group, with 30 cases in each group. The control group was given conventional therapy of hemostasis, dehydration and neurotrophic drugs. The observation group was treated with edaravone on the basis of routine treatment. Observed two groups of patients with cerebral edema changes, awareness recovery related situation. Results After 7 and 14 days of treatment, the area of brain edema in the observation group was less than that of the control group (P <0.05). The Glasgow Coma Scale (GCS) score in both groups was higher than that before treatment, while the acute physiology and chronic health score (APACHE-Ⅱ score) were lower than before treatment (P <0.05), and the improvement in the observation group were more than the control group (P <0.05). Conclusion Edaravone has the effect of eliminating cerebral edema on the treatment of extracerebral trauma and promoting the recovery of cranial nerve function in patients. It is worth widely clinical application.