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目的探讨肝门部胆管癌外科切除的临床价值。方法回顾性分析49例肝门胆管癌病例的临床资料,观察手术方式与患者预后的关系。结果本组49例肝门部胆管癌患者中,根治性切除27例(55.1%),姑息性切除14例(28.6%),无法切除8例(16.3%);根治切除组1、3、5年生存率分别为66.7%,40.7%,25.9%;姑息性切除组1、3、5年生存率分别为28.6%,7.1%,0.0%;无法切除组1年生存率仅为12.5%。术后并发症:胆漏3例(根治性2例,姑息性1例),消化道出血1例。结论肝门部胆管癌的外科切除优于其他治疗方式,而根治性切除是提高生存率的有效方法。
Objective To investigate the clinical value of surgical resection of hilar cholangiocarcinoma. Methods The clinical data of 49 patients with hilar cholangiocarcinoma were retrospectively analyzed. The relationship between the surgical methods and the prognosis of the patients was observed. Results In the group of 49 patients with hilar cholangiocarcinoma, radical resection was performed in 27 cases (55.1%), palliative resection in 14 cases (28.6%) and excision in 8 cases (16.3%). Radical resection group 1,3,5 The annual survival rates were 66.7%, 40.7% and 25.9% respectively. The 1, 3, 5-year survival rates of palliative resection group were 28.6%, 7.1% and 0.0% respectively. The 1-year survival rate of unresectable group was only 12.5%. Postoperative complications: 3 cases of bile leakage (radical 2 cases, palliative 1 case), gastrointestinal bleeding in 1 case. Conclusions Surgical resection of hilar cholangiocarcinoma is superior to other treatment methods. Radical resection is an effective method to improve survival rate.