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目的观察长托宁和阿托品合用救治急性有机磷农药中毒(AOPP)的疗效。方法AOPP患者共88例,采用长托宁与阿托品合用治疗者46例作为治疗组,单用阿托品治疗的42例作为对照组,将两组疗效进行对比观察。结果治疗组在用药次数、胆碱酯酶升高时间、治愈率、住院时间等方面均优于对照组。结论长托宁与阿托品合用治疗AOPP,是理想的抗胆碱药,是一种更符合临床实际的用药方式,值得临床推广应用。
Objective To observe the efficacy of combination of penehyclidine and atropine in the treatment of acute organophosphorus pesticide poisoning (AOPP). Methods AOPP patients, a total of 88 cases, the use of a combination of penehyclidine and atropine in 46 patients as a treatment group, only atropine treatment of 42 patients as a control group, the two groups compared the efficacy of observation. Results The treatment group was superior to the control group in the frequency of medication, the increase of cholinesterase, the cure rate and the length of hospital stay. Conclusions Combined use of penehyclidine hydrochloride and atropine in the treatment of AOPP is an ideal anticholinergic drug. It is a more practical method for clinical use and is worthy of clinical application.