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目的分析福建医科大学附属泉州第一医院2015年1—6月人血清蛋白的临床应用情况,为人血清蛋白的合理用药提供依据。方法收集本院2015年1—6月所有使用过人血清蛋白的住院患者的性别、年龄、住院科室、临床诊断、清蛋白水平、医嘱用药量及用药理由等资料,并结合人血清蛋白说明书、美国医院联合会(UHC)制定的《人血白蛋白、非蛋白胶体及晶体溶液使用指南》及临床公认的清蛋白静脉滴注指征[6]等,对本院人血清蛋白的临床应用进行分析总结,评价其合理性并给出相关建议。结果本院2015年1-6月使用人血清蛋白的住院患者共285例,涉及全院25个科室,其中重症医学科用药总量最多,占23.68%。个人用药量以11~30 g最多,占41.05%;其次是31~60 g,占23.51%。患者用药前血清清蛋白水平在25~30 g/L之间占39.30%,在31~35 g/L之间占8.77%,未检查占1.05%。患者因纠正低蛋白血症使用人血清蛋白的占64.56%。结论本院人血清蛋白的临床应用仍存在不合理现象,需进一步加强管理,以促进临床合理用药。
Objective To analyze the clinical application of human serum albumin from January to June 2015 in Quanzhou First Hospital of Fujian Medical University, and to provide basis for rational use of human serum protein. Methods The data of all the hospitalized patients who used human serum albumin from January to June 2015 in our hospital were collected, such as sex, age, hospitalization, clinical diagnosis, albumin level, prescription dosage, medication rationale and so on. Combined with the human serum protein specification, The clinical use of serum albumin in our hospital is described in the “Guidelines for the Use of Human Albumin, Non-Protein Colloid and Crystal Solutions” developed by the United States Hospital Federation (UHC) and the clinically recognized indication for intravenous infusion of albumin [6] Analyze and summarize, evaluate its rationality and give relevant suggestions. Results A total of 285 hospitalized patients with serum albumin in our hospital from January to June 2015 were involved in 25 departments of the hospital, of which the total amount of medications in the department of critical care was the highest, accounting for 23.68%. The dosage of individual was 11-30 g, accounting for 41.05%, followed by 31-60 g, accounting for 23.51%. Serum albumin levels of patients before treatment accounted for 39.30% between 25 and 30 g / L, accounting for 8.77% between 31 and 35 g / L, accounting for 1.05%. 64.56% of patients used human serum albumin to correct hypoproteinemia. Conclusion The clinical application of serum protein in our hospital still has an unreasonable phenomenon, which needs to be further strengthened to promote the rational use of clinical medicine.