论文部分内容阅读
目的:探讨山莨菪碱、更昔洛韦和西咪替丁治疗小儿秋季腹泻临床效果。方法:选择我院2009年10月～2011年10月秋季腹泻患儿共200例,上述患儿随机分为2组,观察组和对照组。2组患儿均给予静脉补液,纠正脱水、纠正水电解质紊乱,维持酸碱平衡,同时给予蒙脱石散口服,对患儿饮食进行指导。对照组同时给予炎琥宁注射液静脉滴注,每天3～5mg/kg。观察组患儿给予更昔洛韦、上莨菪碱和西咪替丁静脉滴注。其中更昔洛韦每天10mg/kg、上莨菪碱每天0.15mg/kg、西咪替丁每天10mg/kg。2组患儿均连续治疗5天。治疗期间观察2组患儿大便改变情况,记录止泻时间和退热时间。结果:观察组止泻时间和退热时间均早于对照组,差异有统计学意义(P<0.05);观察组总有效率显著高于对照组,差异有统计学意义(P<0.05)。结论:山莨菪碱、更昔洛韦和西咪替丁治疗小儿秋季腹泻临床效果显著,值得借鉴。
Objective: To investigate the clinical effects of anisodamine, ganciclovir and cimetidine in the treatment of infantile autumn diarrhea. Methods: A total of 200 children with diarrhea in our hospital from October 2009 to October 2011 were selected and randomly divided into two groups: observation group and control group. 2 groups of children were given intravenous rehydration, correct dehydration, correct water and electrolyte imbalance, maintain acid-base balance, while given oral montmorillonite, the children’s diet guidance. The control group was given Yanhuning injection intravenously, 3 ~ 5mg / kg daily. Patients in the observation group were given ganciclovir, scopolamine and cimetidine intravenously. Among them, 10 mg / kg of ganciclovir daily, 0.15 mg / kg of scopolamine daily and 10 mg / kg of cimetidine daily. Two groups of children were treated for 5 consecutive days. During treatment, the changes of stool in two groups were observed, and the diarrhea time and antipyretic time were recorded. Results: The antidiarrheal time and antipyretic time of the observation group were earlier than that of the control group (P <0.05). The total effective rate of the observation group was significantly higher than that of the control group (P <0.05). Conclusion: Anisodamine, ganciclovir and cimetidine treatment of pediatric fall diarrhea clinical effect is significant, it is worth learning.