碳/碳复合材料表面粗糙度对成骨细胞生长行为的影响

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采用化学气相沉积工艺制备了碳/碳(C/C)复合材料,用表面轮廓仪检测了表面粗糙度,用MG-63成骨细胞进行了细胞试验,研究了C/C复合材料表面粗糙度对成骨细胞形貌、粘附和增殖的影响规律.结果表明:C/C复合材料表面粗糙度越高则成骨细胞在其表面的粘附率越高,增殖率越低;C/C复合材料表面粗糙度对成骨细胞的生长方向和形貌具有诱导作用,粗糙度越高则方向诱导作用越明显,且细胞附着形貌呈梭形或长条状,立体感强,反之成骨细胞则呈现片状,铺展状态好.
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