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目的探讨中医院临床鲍曼不动杆菌感染现状、耐药性及预防措施。方法回顾性分析射洪县中医院2013—2015年收治的住院患者临床标本中分离的鲍曼不动杆菌62株,应用康泰微生物鉴定系统对临床分离出的细菌进行鉴定和药物敏感试验。结果在临床标本中以痰标本分离率最高,伤口分泌物和腹腔引流液次之。感染分布的病房以呼吸内科为主,其次为脑外、肿瘤内科。多重耐药比率ICU占第一位,其次为脑外科、骨科。鲍曼不动杆菌感染率和多重耐药率均呈上升趋势。药敏结果显示,鲍曼不动杆菌对青霉素类、B内酰胺酶抑制剂的混合制剂有较高的耐药性,对碳青霉烯类耐药性最低,其次是头孢哌酮、磷霉素和左氧氟沙星。结论鲍曼不动杆菌感染率和耐药率不断上升,临床医生应高度重视,做好各种预防措施,以减少医院感染发生及多重耐药菌株出现。
Objective To investigate the clinical status, drug resistance and prevention of Acinetobacter baumannii infection in Chinese medicine hospital. Methods A retrospective analysis of 62 cases of Acinetobacter baumannii isolated from clinical specimens of hospitalized patients in Shehong County Chinese Medicine Hospital from 2013 to 2015 was performed. The Kangtai microbial identification system was used to identify the bacteria isolated from the clinical samples and drug susceptibility testing. The results in the clinical specimens to sputum specimens the highest separation rate, followed by wound secretions and peritoneal drainage. Ward infected with respiratory medicine-based, followed by brain, oncology. Multiple drug resistance rate ICU accounted for first place, followed by brain surgery, orthopedics. Acinetobacter baumannii infection rate and multiple drug resistance rates showed an upward trend. The results of drug sensitivity showed that Acinetobacter baumannii had higher resistance to penicillin and B lactamase inhibitors, the lowest resistance to carbapenems, followed by cefoperazone, Su and levofloxacin. Conclusion Acinetobacter baumannii infection rate and resistance rate are rising, clinicians should attach great importance to a variety of preventive measures to reduce the occurrence of nosocomial infections and the emergence of multi-drug resistant strains.