动脉粥样硬化是一种炎症性病变,急性冠脉综合征的发生、发展更与炎症密切相关。C反应蛋白是一种典型的炎症急性相反应蛋白,其血浆水平的高低可直接反映冠状动脉粥样硬化斑块的炎症状态及稳定程度。目前,把血浆C反应蛋白作为急性冠脉综合征患者危险分层和预后判定指标的临床价值已逐渐得到认同,但最新研究发现,新蝶呤和脑利钠肽等对急性冠脉综合征患者的预后评估可能较C反应蛋白更为特异而敏感。 Atherosclerosis is an inflammatory disease, the occurrence of acute coronary syndrome, development and inflammation are closely related. C-reactive protein is a typical inflammation of the acute phase protein, the level of plasma can directly reflect the coronary atherosclerotic plaque inflammation and stability. Currently, the clinical value of plasma C-reactive protein as a risk stratification and prognostic indicator in patients with acute coronary syndrome has gradually been recognized, but the latest study found that neopterin and brain natriuretic peptide in patients with acute coronary syndrome The prognostic assessment may be more specific and sensitive than C-reactive protein.