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为广西壮族自治区将乙型肝炎 (乙肝 )疫苗纳入儿童计划免疫的实施提供本底资料 ,采用多阶段整群系统随机抽样方法 ,于 2 0 0 3年调查了 0～ 3岁儿童 5 6 70人 ,儿童母亲 12 16人。结果显示 :0～ 3岁儿童乙肝疫苗接种率、全程接种率和首针及时接种率分别为 76 16 %、73 4 4 %、32 6 6 % ;乙肝病毒表面抗原 (HBsAg)与抗体 (抗 HBs)、乙肝病毒核心抗体 (抗 HBc)阳性率分别为 3 37%、4 0 18%、5 17%。与 1992年调查结果相比较 ,乙肝疫苗接种率提高了 77 6 1% ,HBsAg携带率由 9 6 8%降至 3 37% ,保护率为 6 5 19%。首针及时接种、全程接种乙肝疫苗儿童的HBsAg、抗 HBc阳性率非常显著地低于未接种的儿童 ,HBsAg阳性母亲儿童的HBsAg、抗 HBc阳性率非常显著地高于其他儿童。提高首针及时接种率、全程接种率 ,降低阳性母亲儿童的HBsAg、抗 HBc阳性率成为今后乙肝控制工作的重点
Provided background information for the implementation of planned immunization for hepatitis B vaccine in Guangxi Zhuang Autonomous Region and conducted a random sampling of multistage cluster system to investigate the prevalence of 5 6 70 children 0-3 years old in 2003 , 12,16 children and mothers. The results showed that the vaccination rate, the full vaccination rate and the first inoculation rate of children aged 0-3 years were 76 16%, 73 4 4% and 32 6 6%, respectively. HBsAg and anti-HBs ), The positive rate of HBcAg (anti-HBc) was 377%, 40%, 51% respectively. Compared with the 1992 survey results, the hepatitis B vaccination rate increased by 77 61%, the HBsAg carrier rate decreased from 96.8% to 377%, and the protection rate was 65.19%. The first needles were inoculated in time. The positive rate of anti-HBc in HBsAg-vaccinated children was significantly lower than that in unvaccinated children. The positive rate of anti-HBc in HBsAg-positive mothers was significantly higher than that in other children. Promote the first needles promptly inoculation rate, the entire vaccination rate, reduce the positive mother and child HBsAg, anti-HBc positive rate has become the focus of future hepatitis B control