甲氨蝶呤是常用的抗代谢类抗肿瘤药 ,系叶酸拮抗剂 ,能抑制二氢叶酸还原酶 ,干扰ＤＮＡ的合成 ,从而使肿瘤细胞增生受抑制 ,用于急性白血病 ,尤其是急性淋巴性白血病、绒毛膜上皮癌及恶性葡萄胎等效果较好。对头颈部肿瘤、乳腺癌、肺癌、肝癌及盆腔肿瘤也有一定疗效。采用动脉 Methotrexate is a commonly used anti-tumor anti-tumor drug, a folic acid antagonist, can inhibit dihydrofolate reductase, interfering with DNA synthesis, thereby inhibiting the proliferation of tumor cells for acute leukemia, especially acute lymphoid Leukemia, choriocarcinoma and malignant mole better. Head and neck cancer, breast cancer, lung cancer, liver cancer and pelvic tumors have a certain effect. Arteries