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患儿,男,13a,因患“扁桃体炎”在当地医院给予青霉素等治疗4d,仍有低热,当地医院照胸片疑肺门肿大,考虑“肺结核”给予口服异烟肼0.2/d,利福平0.2/d 抗痨,同时静点青霉素、氨苄青霉素,服药当天起患儿出现高热,均在服药后1h 出现,体温高达39.5~40.5℃,且物理及药物降温无效,一般在10~12h 后自行热退。高热时常伴有畏寒、头痛、心慌、胸闷等症状,但无皮疹、咳嗽及晕厥。先后加用氧哌嗪青霉素、先锋必及吡嗪酰胺等多种抗炎抗痨药物治疗3mo 余均无效,体温每天均在39℃以
Children, male, 13a, suffering from “tonsillitis” in the local hospital for penicillin treatment 4d, there is still fever, the local hospital according to chest suspected swollen hilar, consider “pulmonary tuberculosis” given oral isoniazid 0.2 / d, Rifampicin 0.2 / d anti-tuberculosis, while static point penicillin, ampicillin, high fever on the day of taking the medication, were in 1h after taking the drug, body temperature as high as 39.5 ~ 40.5 ℃, and physical and drug cooling is invalid, After 12h their own thermal retreat. High fever often accompanied by chills, headache, palpitation, chest tightness and other symptoms, but no rash, cough and fainting. Has added with piperazine penicillin, Pioneer and pyrazinamide and other anti-inflammatory anti-tuberculosis drugs 3mo more than ineffective, body temperature every day at 39 ℃ to