我们利用头低位(-6°)卧床作为模拟失重模型进行了6名男性志愿者卧床一周的实验,目的是分析卧床条件下人尿肾上腺素(E)、去甲肾上腺素(NE)昼夜节律特点以及心血管功能的反应。结果表明,卧床期E、NE 及E+NE 昼夜节律的水平和幅度显著降低;儿茶酚胺(CA)各成份的相位发生了内部解离,上述变化在卧床后5天内皆恢复正常。说明头低位卧床能影响人尿CA 的昼夜节律。 We used a low bedside (-6 °) bed as a model for simulated weight loss to conduct a one-week ambulatory trial of six male volunteers in order to analyze the circadian rhythm of human epinephrine (E) and norepinephrine (NE) under bed-ridden conditions As well as cardiovascular response. The results showed that the levels and amplitudes of circadian rhythm of E, NE and E + NE in bed rest decreased significantly, and the phases of catecholamine (CA) components were internally dissociated. These changes returned to normal within 5 days after bed rest. Description head low bed rest can affect the circadian rhythm of human urine CA.