庆大霉素为氨基糖甙类抗生素,在基层有滥用现象,肾毒性的发生也随之增多,应当引起临床医师(特别是基层)的足够重视。肾损害的发生率和药量及用药时间有关,在治疗剂量时,发生率2～30％,若增加剂量与延长疗程,可高达66％。有人报道,即使是治疗剂量,用7～10天,100％的患者均有不同程度的肾小球和肾小管功能受损。 Gentamicin aminoglycoside antibiotics, abused at the grassroots level, the incidence of nephrotoxicity will also increase, clinicians should be caused, especially grass-roots attention. The incidence of renal damage and the amount of medication and medication time, the dose at the time of treatment, the incidence of 2 to 30%, if increased dose and prolonged course of treatment, up to 66%. It was reported that, even for therapeutic doses, glomerular and tubular functions were impaired to varying degrees in 100% of patients over 7 to 10 days.