论文部分内容阅读
冠脉内溶栓治疗急性心肌梗塞(AMI)已经证实在限制心肌坏死,保证左室功能和提高生存率方面是有效的。本研究评价冠脉内溶栓成功率的昼夜变化,因为有人报告,在早晨数小时内,纤维蛋白溶酶原激活剂抑制剂的活性显著增加。 完全闭塞相关冠脉血管,第一次AMI的60名患者在胸痛6小时内,进行冠脉内溶栓。男45人,女15人(平均年龄60岁)。所有病人持续胸痛≥30分钟,有顽固性心肌缺血,用过硝酸盐治疗,心电图2个导联以上ST段抬高≥0.1mv。
Intracoronary thrombolysis for acute myocardial infarction (AMI) has been shown to be effective in limiting myocardial necrosis, ensuring left ventricular function and improving survival. This study evaluated the diurnal change in success rate of intra-coronary thrombolysis as it was reported that the activity of plasminogen activator inhibitor was significantly increased in the morning hours. Totally occluded coronary arteries, 60 patients in the first AMI underwent intracoronary thrombolysis within 6 hours of chest pain. 45 men and 15 women (average age 60 years). All patients sustained chest pain ≥ 30 minutes, with refractory myocardial ischemia, nitrite therapy, electrocardiogram more than 2 leads ST segment elevation ≥ 0.1mv.