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目的分析中老年人甲状腺结节病变的特点。方法回顾分析我院45~79岁健康体检的甲状腺结节患者528例的临床资料,根据年龄段分为二组:中年组年龄45~59岁,共196例;老年组年龄60~79岁,共332例。全部行甲状腺彩色超声检查。电化学发光法检测甲状腺功能及甲状腺抗体。结果中老年甲状腺结节以单发、直径<1.0cm为主。甲状腺功能正常者271例;原发性临床甲减患者51例;原发性亚临床甲减患者206例。其中,老年组女性亚临床甲减发生率较中年组女性明显升高,差异有统计学意义(P<0.05);老年组亚临床甲减总发生率高达42.47%,较中年组明显升高(P<0.05)。原发性甲减患者甲状腺自身抗体阳性率高达47.86%。结论与中年人群相比,老年人群具有更高的甲状腺结节发生率且易合并原发性甲减;原发性甲减患者甲状腺自身抗体阳性率明显升高。
Objective To analyze the characteristics of thyroid nodules in the elderly. Methods The clinical data of 528 thyroid nodules from 45 to 79 years old in our hospital were retrospectively analyzed. According to the age group, they were divided into two groups: the middle age group was 45 to 59 years old, with a total of 196 cases; the aged group was 60 to 79 years old , A total of 332 cases. Thyroid color ultrasound examination. Electrochemiluminescence Detection of Thyroid Function and Thyroid Antibody. Results middle-aged thyroid nodules to single, diameter <1.0cm based. 271 cases of normal thyroid function; 51 cases of primary clinical hypothyroidism; 206 cases of primary subclinical hypothyroidism. Among them, the incidence of subclinical hypothyroidism in the elderly group was significantly higher than that in the middle-aged group (P <0.05). The incidence of subclinical hypothyroidism in the elderly group was as high as 42.47%, significantly higher than that in the middle-aged group High (P <0.05). The incidence of thyroid autoantibodies in patients with primary hypothyroidism was as high as 47.86%. Conclusion Compared with the middle-aged population, the elderly population has a higher incidence of thyroid nodules and is predisposed to primary hypothyroidism. The positive rate of thyroid autoantibodies in patients with primary hypothyroidism is significantly higher.