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患者女,60岁.躯干及四肢散在红斑、丘疹4月余.皮损初起为暗红色丘疹,以后中央逐渐萎缩,最终形成瓷白色瘢痕,上覆细小鳞屑,周围隆起伴红晕.皮损组织病理示:表皮角化不全,基底细胞液化变性,真皮乳头层轻度胶原纤维变性,伴真皮浅层小血管周围淋巴单个核细胞浸润.诊断:恶性萎缩性丘疹病.糖皮质激素治疗无效,阿司匹林治疗有效.“,”A 60-year-old female presented with scattered erythema and papules on her trunk and limbs for more than 4 months.At the beginning,the skin lesions were dark red papules,with the central papules gradually shrinking,and it had formed ultimately a porcelain-white scar and covered with small scales,surrounded by the pink edematous border.Pathology showed epidermal parakeratosis,local liquifaction of basal cells,degeneration of collagen fibers in papillary layer,and perivascular lymphocyte infiltration.The diagnosis of malignant atrophic papulosis was made.Steroids were ineffective so aspirin was used successfully.