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上海市的百日咳发病率曾经高达1150.16/10万,使用百白破混合制剂(DPT)免疫及全程免疫接种率提高至90%后,使发病得到了有效控制.DPT的免疫学效果观察显示.免疫后较免疫前抗体增长40倍以上,阳转率和达保护抗体水平率分别高至90%和85%,吸附DPT的保护率约为96%.由此可见,有效的疫苗和高质量的免疫接种是控制百日咳流行的关键措施。
The prevalence of whooping cough in Shanghai was as high as 1150.16 / 100000. With the DPT immunization and the whole immunization coverage increased to 90%, the incidence was effectively controlled. The immunological effect of DPT was observed. After immunization, the antibody before immunization increased more than 40 times, the positive conversion rate and the level of protective antibody reached 90% and 85% respectively, and the DPT adsorption rate was about 96%. This shows that effective vaccines and high-quality immunization are the key measures to control the prevalence of whooping cough.