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依据传递不平衡法(TDT)对上海地区55个2型糖尿病家系进行磺脲受体1(SUR1)基因多态性分析及临床表型联系分析,未发现SUR1基因的多态性和突变与上海地区2型糖尿病连锁的证据,但其对胰岛素、C肽水平有一定影响。
According to the transmission imbalance (TDT) analysis of the SUR1 gene polymorphism and clinical phenotypic relationship in 55 type 2 diabetic pedigrees in Shanghai, we found no association between SUR1 gene polymorphism and mutations in Shanghai Regional type 2 diabetes, but its effect on insulin and C-peptide levels.