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目的探讨分析胸膜活检结合ADA联合检测在结核性胸膜炎患者中诊断意义。方法以本院2010年11月~2013年11月收治的58名结核性胸膜炎确诊患者为研究对象,进行胸膜活检及胸水腺苷脱氨酶(adenosine delaminate,ADA)检测,计算其诊断阳性率并进行分析。结果通过胸膜活检诊断阳性例数为33例,诊断阳性率为56.9%;通过ADA检测诊断阳性例数为41例,诊断阳性率为70.7%;胸膜活检结合ADA联合检测阳性例数为54例,诊断阳性率为93.1%,其高于单纯胸膜活检(χ2=18.4,P<0.05)和单纯ADA检测(χ2=8.37,P<0.05),差异有统计学意义。结论胸膜活检结合ADA联合检测能有效的提高结核性胸膜炎患者的阳性检出率,具有较高的结核性胸膜炎临床诊断价值,值得广泛应用与推广。
Objective To investigate the diagnostic significance of combined pleural biopsy and ADA in patients with tuberculous pleurisy. Methods Fifty-eight patients with tuberculous pleurisy admitted from November 2010 to November 2013 in our hospital were enrolled in this study. Pleural biopsy and adenosine delaminate (ADA) tests were performed to evaluate the diagnostic positive rate Analyze. Results The positive cases were diagnosed by pleural biopsy in 33 cases and the positive rate was 56.9%. The positive cases diagnosed by ADA were 41 cases and the positive rate was 70.7%. The positive cases of pleural biopsy combined with ADA were 54 cases, The positive rate of diagnosis was 93.1%, which was higher than simple pleural biopsy (χ2 = 18.4, P <0.05) and simple ADA (χ2 = 8.37, P <0.05). Conclusions Pleural biopsy combined with ADA can effectively improve the positive detection rate of tuberculous pleurisy patients and has high clinical diagnostic value of tuberculous pleurisy. It is worth widely applying and popularizing.