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有些人认为,恶性细胞的种种癌的特性,起因于染色体或染色质功能的改变。美国国家肿瘤研究所的狄保罗(Dipaolo)等,单独或合并地使用了各种物理的、化学的或病毒的致癌剂以及非致癌剂,在体外测定了它们对细胞染色体的直接效应和远期效应。他们发现,加了致癌剂后,其直接效应可以是染色单体型畸变,以及染色体型畸变。究竟这些
Some people think that the characteristics of various cancers of malignant cells are due to changes in chromosome or chromatin function. Dipaolo et al. of the National Cancer Institute of the United States used a variety of physical, chemical or viral carcinogens and non-carcinogenic agents, either alone or in combination, to determine their direct effects on cell chromosomes and their long-term in vitro. effect. They found that after adding carcinogens, their direct effects could be chromatid aberrations and chromosomal aberrations. Exactly what