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目的对比分析标准大骨瓣减压术联合选择性脑局部亚低温与单纯大骨瓣减压术对重型颅脑损伤的临床疗效。方法选取84例重型颅脑损伤住院患者,随机分为两组,给予不同的治疗方法,比较两组患者颅内压变化情况、预后效果及并发症。结果两组患者术前和术后即刻颅内压比较差异未见统计学意义(P>0.05),观察组预后效果显著优于对照组(P<0.05),除硬膜下积液,两组患者其余并发症比较差异未见统计学意义(P>0.05)。结论标准大骨瓣减压术联合选择性脑局部亚低温治疗重型颅脑损伤,能够有效降低颅内压,改善预后,但要考虑硬膜下腔积液的发生。
Objective To compare and analyze the clinical curative effect of standard decompressive craniectomy combined with selective local hypothermia of the brain and decompressive craniectomy alone on severe craniocerebral injury. Methods Eighty-four patients with severe craniocerebral injury were selected and randomly divided into two groups. Different treatment methods were given. The changes of intracranial pressure, prognosis and complications were compared between the two groups. Results There was no significant difference in intracranial pressure between the two groups before and immediately after operation (P> 0.05). The prognosis of the observation group was significantly better than that of the control group (P <0.05). In addition to subdural effusion, There was no significant difference in the remaining complications (P> 0.05). Conclusions The treatment of severe craniocerebral injury with standard decompressive craniectomy combined with selective brain hypothermia can effectively reduce intracranial pressure and improve prognosis, but the occurrence of subdural effusion should be considered.