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弓形体脑炎(TE)已成为艾滋病患者一种重要的、威胁生命的机会性感染。在艾滋病流行前,TE 少见,自1981年6月~1985年11月间报告给疾病控制中心的 TE 已有508例。本文对31个医疗中心自1978年1月以来由组织学证实并接受化疗的61例艾滋病伴TE 患者的疗效进行了评价。61例病人的平均年龄36岁(20~58岁),男54例,女7例,男性同性恋38例,静脉药瘾者10例,男性同性恋兼静脉药瘾者2例,7例出生于海地,1例曾接受输血,1例为艾滋病高危人群的异性接触者,2例未注明危险因素。TE 发病无季节性变化。症状和体征:常见头痛(27例)、定向力障碍(23例)、癫痫(22例)和偏瘫(19例);发热者较少(6例)。最初临床评
Toxoplasma encephalitis (TE) has become an important, life-threatening, opportunistic infection in people with AIDS. Prior to the AIDS epidemic, TE was uncommon and 508 cases were reported to the Centers for Disease Control and Prevention from June 1981 to November 1985. This article reviews the efficacy of 61 HIV patients with TE confirmed by histology and chemotherapy in 31 centers since January 1978. The average age of 61 patients was 36 years old (20-58 years). There were 54 males and 7 females, 38 were homosexual men, 10 were intravenous drug addicts, 2 were male homosexuality and intravenous drug addicts, and 7 were born in Haiti , One had heterosexual contact who had received blood transfusion and one was at high risk for HIV and two did not indicate any risk factors. No seasonal changes in the incidence of TE. Symptoms and signs: Common headache (n = 27), disorientation (n = 23), epilepsy (n = 22) and hemiplegia (n = 19); Fever (6). Initial clinical evaluation