法国鼻息肉的流行

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在法国因缺乏对基础人群的诊断工具,从未建立过鼻息肉流行的数据,故在基础人群的随机样本中使用了新近有效的调查表/规则系统(90%特殊性和敏感性),用目前的横断面、病例-对照研究确定鼻息肉的流行,并描述鼻息肉流行病学的主要方面。总共筛选了10033名受试者(年龄≥18岁)。在鉴定了有或无鼻息肉的受试者后,调查表提交鼻息肉患者做进一步的数据采集。对照者是无鼻息肉的个体,性别和年龄与鼻息肉患者配对。结果为,鼻息肉的流行为2.11%(95%C I:1.83~2.39),鼻息肉患者(n=212,45%男性)年龄(49.7±17.6)岁,未观察到性别优势,但鼻息肉倾向于随着年龄的增加而增加。鼻症状平均持续的时间为(22.4±15.7)年,145名患者因鼻症状曾就医,77.2%的已看过专科医生,且18.6%的被诊断为鼻息肉,39.9%的鼻息肉患者鼻溢,鼻阻塞的30.8%,嗅觉丧失28.9%,只有6.9%的报告面部不舒服,而24.6%的陈述一般性不舒服。大多数鼻息肉患者(61.3%)曾经药物治疗,主要用鼻喷雾剂(76.9%)。目前的研究提供了法国鼻息肉流行病学有效的和可靠的资料,采集的信息大多数以公开的国际资料为依据。 In France, which has never established epidemiological data on nasal polyps due to a lack of diagnostic tools for the underlying population, a recently validated questionnaire / rule system (90% specificity and sensitivity) was used in the random sample of the primary population with Current cross-sectional, case-control studies determine the prevalence of nasal polyps and describe the major aspects of the epidemiology of nasal polyps. A total of 10033 subjects were screened (age ≥18 years). After identifying subjects with or without polyps, the questionnaire was submitted to patients with nasal polyps for further data collection. Control subjects were non-nasal polyps, sex and age paired with patients with nasal polyps. The prevalence of nasal polyps was 2.11% (95% CI: 1.83 to 2.39) and the age of the nasal polyps (n = 212, 45% of males) was (49.7 ± 17.6) years, with no gender predominance, but the prevalence of nasal polyps Increase with age. The average duration of nasal symptoms was (22.4 ± 15.7) years, 145 patients had been hospitalized for nasal symptoms, 77.2% had seen a specialist, 18.6% had been diagnosed with nasal polyps and 39.9% had nasal polyps , 30.8% of nasal obstruction, 28.9% loss of smell, and only 6.9% reported facial discomfort, while 24.6% reported general discomfort. Most patients with nasal polyps (61.3%) have been treated with nasal sprays (76.9%). The current study provides epidemiologically valid and reliable information on French nasal polyps, the majority of which is based on publicly available international information.
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