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目的探讨PCT和SAA在老年细菌性肺炎中的应用价值。方法选取2016年4月-7月本院治疗的肺炎患者,分为细菌性肺炎组96例和病毒性肺炎组89例,另选取健康体检者100例为对照组,测定3组患者的PCT和SAA水平,对细菌性肺炎组治疗前后PCT和SAA水平进行比较,分析两者在老年细菌性肺炎中的诊断效率。结果细菌性肺炎组PCT和SAA水平明显高于病毒性肺炎组和对照组,治疗后PCT和SAA均显著降低,差异均有统计学意义(P<0.05)。细菌性肺炎组PCT和SAA的阳性率高于病毒感染组和对照组,差异均有统计学意义(P<0.05);PCT诊断细菌性肺炎的特异度、阳性预测值、阴性预测值均高于SAA,两者水平呈正相关(r=0.794,P<0.01)。结论检测PCT和SAA对老年细菌性肺炎的早期诊断和指导用药具有指导意义,诊断效率PCT优于SAA。
Objective To investigate the value of PCT and SAA in the treatment of bacterial pneumonia in the elderly. Methods A total of 96 patients with pneumonia in our hospital from April to July 2016 were divided into bacterial pneumonia group (n = 96) and viral pneumonia group (n = 89). Another 100 healthy subjects were selected as the control group. The PCT and SAA levels before and after bacterial pneumonia in patients with PCT and SAA levels were compared, the two in the diagnosis of bacterial pneumonia in elderly efficiency. Results The levels of PCT and SAA in bacterial pneumonia group were significantly higher than those in viral pneumonia group and control group. The PCT and SAA were significantly decreased after treatment (P <0.05). The positive rates of PCT and SAA in bacterial pneumonia group were higher than those in virus-infected group and control group (P <0.05). The specificity, positive predictive value and negative predictive value of PCT diagnosis of bacterial pneumonia were higher than those of PCT SAA, the two levels were positively correlated (r = 0.794, P <0.01). Conclusion Detection of PCT and SAA is of guiding significance in the early diagnosis and guidance of elderly patients with bacterial pneumonia. The diagnostic efficiency of PCT is better than that of SAA.