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目的：观察米非司酮配伍米索前列醇软化宫颈的效果。方法：对 30例钳刮术者于术前用药软化宫颈并与 30例对照组进行比较。数据用卡方及 t检验判定其显著性。结果：用药组宫颈软化率为 100％，对照组软化率为 36. 7％，两组比较有显著性差异 (P<0. 01)。术中出血量两组有显著性差异 (P<0. 01)。结论：米非司酮与米索前列醇序贯给药软化宫颈效果较好，副作用小，值得推广应用。
Objective: To observe the effect of mifepristone and misoprostol in softening cervix. Methods: 30 cases of forceps curettage before surgery to soften the cervix and compared with 30 cases of control group. Data using chi-square test and t test to determine its significance. Results: Cervical softening rate was 100% in the treatment group, the control group softening rate was 36.7%, there was significant difference between the two groups (P <0.01). The amount of bleeding during surgery was significantly different between the two groups (P <0.01). Conclusions: Mifepristone and misoprostol are effective in sequential treatment of cervix softening, with less side effects, which is worth popularizing and applying.