论文部分内容阅读
目的探讨牙周基础治疗联合干黄茶乳剂对慢性牙周炎患者龈沟液IL-6、IL-10、IL-17、IFN-γ、TNF-α表达的影响。方法选取2014年7月-2016年8月本院慢性牙周炎患者86例,分为对照组和研究组,各43例。对照组采用牙周基础治疗,研究组采用牙周基础治疗联合干黄茶乳剂,均持续治疗3个月,比较两组临床疗效,IL-6、IL-10、IL-17、IFN-γ、TNF-α表达水平及牙周指数相关指标水平、症候群评分变化情况。结果研究组治疗总有效率高于对照组;治疗后研究组IL-6、TNF-α、IL-17、IFN-γ水平低于对照组,IL-10水平高于对照组;治疗后研究组PD、PLI、SBI、CAL水平低于对照组;治疗后研究组主症候群评分及次症候群评分低于对照组,上述差异均有统计学意义(P<0.05)。结论牙周基础治疗联合干黄茶乳剂治疗慢性牙周炎效果显著,可有效改善患者牙周状况及临床症状,降低龈沟液IL-6、IL-10、IL-17、IFN-γ、TNF-α表达水平,提高治疗效果,具有推广价值。
Objective To investigate the effects of periodontal treatment with dry yellow tea emulsion on the expression of IL-6, IL-10, IL-17, IFN-γ and TNF-α in gingival crevicular fluid in patients with chronic periodontitis. Methods Totally 86 patients with chronic periodontitis in our hospital from July 2014 to August 2016 were divided into control group and study group, with 43 cases in each group. The control group was treated with periodontal basic treatment. The study group was treated with periodontal basic treatment combined with dry yellow tea emulsion for 3 months. The clinical efficacy, IL-6, IL-10, IL-17, IFN- TNF-αexpression levels and periodontal index related indicators, symptom score changes. Results The total effective rate of the study group was higher than that of the control group. After treatment, the levels of IL-6, TNF-α, IL-17 and IFN-γ in the study group were lower than those in the control group The levels of PD, PLI, SBI and CAL in the study group were lower than those in the control group. The scores of main syndromes and sub-syndromes in the study group were lower than those in the control group after treatment. The differences were statistically significant (P <0.05). Conclusion The combination of periodontal treatment and dry yellow tea emulsion can significantly improve the periodontal status and clinical symptoms of patients with chronic periodontitis and reduce the levels of IL-6, IL-10, IL-17, IFN-γ, TNF -α expression, improve the therapeutic effect, with the promotion of value.