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伤害性感受是通过交感和运动神经来接受中枢神经系统的调控。最近推出的有关伤害性感受相关中枢核团的研究进展。表现在:运用能够表达独特标记蛋白的伪狂犬病毒重组体来进行多突触示踪,以及开发在独特启动子调控下能够表达荧光蛋白的转基因小鼠作为研究工具。该文就转突触示踪技术与伤害性感受相关中枢核团的研究进展进行综述。
Nociceptives are mediated through the sympathetic and motor nerves to the central nervous system. Recent advances in the research of nociceptive central nervous system. This is demonstrated by poly synaptic tracing using a pseudorabies virus recombinant that expresses a unique marker protein and the development of transgenic mice capable of expressing a fluorescent protein under the control of a unique promoter as a research tool. This review summarizes the research progress of synaptic tracing techniques and the central nuclei involved in nociception.