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目的探讨老年原发性高血压晨峰(MBPS)现象对靶器官损害的影响。方法原发性高血压患者58例,依24 h动态血压分MBPS组(30例)和非MBPS组(28例)。所有对象进行心脏和颈动脉超声检查,计算左室质量指数(LVMI)、颈动脉内膜中层厚度(IMT)。结果 MBPS组24 h、白昼以及夜间平均收缩压、脉压均较非MBPS组高(P<0.05),MBPS组的LVMI及左右两侧颈动脉IMT均明显高于非MBPS组(P<0.05)。结论老年原发性高血压患者具有MBPS现象者有明显的靶器官损害。
Objective To investigate the effect of MBPS on target organ damage in elderly patients with essential hypertension. Methods Fifty-eight patients with essential hypertension were divided into two groups based on 24-h ambulatory blood pressure (MBPS) group (30 cases) and non-MBPS group (28 cases). All subjects underwent heart and carotid ultrasonography to calculate left ventricular mass index (LVMI) and carotid artery intima-media thickness (IMT). Results The average systolic blood pressure and pulse pressure in MBPS group were higher than those in non-MBPS group (P <0.05) at 24 h, daytime and nighttime respectively. The LVMI and carotid IMT in both MBPS group and MBPS group were significantly higher than those in non-MBPS group (P <0.05) . Conclusion MBPS in elderly patients with essential hypertension have obvious target organ damage.