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目的探讨细菌性阴道炎(BV)与女性免疫性不孕的相关性。方法选取我院收治的210例不孕患者,其中细菌性阴道炎不孕患者110例,非细菌性阴道炎患者不孕患者100例,通过检测不孕妇女的抗精子抗体(AsAb)、抗子宫内膜抗体(EmAb)及抗心磷脂抗体(ACA),并与26例健康孕妇对比,分析BV与女性免疫性不孕的关系。结果 BV组在宫颈粘液AsAb、EmAb方面与非BV组比较差异明显(P<0.05)。结论 BV与免疫性不孕的形成和发展有一定关系,特别与AsAb的产生有一定相关性,可使反复自然流产增加。
Objective To investigate the relationship between bacterial vaginosis (BV) and female infertility. Methods A total of 210 infertile patients were enrolled in our hospital, including 110 cases of bacterial vaginosis infertility and 100 cases of infertility of non-bacterial vaginitis. By detecting anti-sperm antibodies (AsAb) and anti-uterine (EmAb) and anti-cardiolipin antibodies (ACA) were compared with 26 healthy pregnant women to analyze the relationship between BV and female immunological infertility. Results The BV group had significant differences in AsAb and EmAb between cervical mucus and non-BV group (P <0.05). Conclusions BV is related to the formation and development of immune infertility, especially to AsAb, which may lead to the increase of recurrent spontaneous abortion.