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目的探讨妊娠期糖耐量受损(GIGT)对围生期的影响。方法对101例GIGT孕妇(GIGT组),82例妊娠期糖尿病(GDM)孕妇(GDM组),同期100例糖耐量正常孕妇(对照组)及围生儿结局进行比较。结果GIGT组胎膜早破(13/101)、巨大儿(20/101)、胎儿窘迫(9/101)、羊水过多(10/101)及手术产率(57/101)与对照组比较显著增高(P﹤0.05),新生儿低血糖发生率高于对照组(P﹤0.05)。GIGT组与GDM组比较妊娠期高血压疾病、早产的发生率有显著性差异(P﹤0.05)。结论GIGT与GDM均是影响孕妇及围生儿结局的重要因素,应加强妊娠期不同程度糖耐量异常的监测和管理,减少母婴并发症的发生。
Objective To investigate the effect of gestational impaired glucose tolerance (GIGT) on perinatal period. Methods A total of 101 GIGT pregnant women (GIGT group), 82 pregnant women with gestational diabetes (GDM), 100 pregnant women with normal glucose tolerance (control group) and perinatal outcome were compared. Results Compared with the control group, the premature rupture of membranes (13/101), macrosomia (20/101), fetal distress (9/101), polyhydramnios (10/101) and operative rate (57/101) (P <0.05), the incidence of neonatal hypoglycemia was higher than that of the control group (P <0.05). GIGT group compared with GDM group of hypertensive disorder complicating pregnancy, the incidence of preterm birth was significantly different (P <0.05). Conclusions Both GIGT and GDM are important factors affecting the outcomes of pregnant women and perinatal children. Monitoring and management of abnormal glucose tolerance during pregnancy should be strengthened to reduce the incidence of maternal and infant complications.