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蔡某,女,33岁,于1989年8月中旬无特殊诱因出现月经过多、牙龈出血、伴不规则发烧,于9月16日至我院就医。检查WBC0.35×10~9/L,Hb55g/L、BPC42×10~9/L。查体:T36℃,贫血貌,全身浅表淋巴结不肿大,皮肤及粘膜无黄染、出血点,睑结膜苍白、两肺呼吸音清、腹软、肝脾未及。骨髓象:增生明显话跃,粒:红=8.5:1细颗粒型早幼粒细胞64％可见Auer氏小体,Pox强阳性,α—醋酸荼酯酶(+),氟化钠抑制试验(-)确诊为APL。入院第三天开始服用RASO/mg日。在RA开始治疗第三天,全身皮肤及粘膜出现散在出血点及紫
Cai, female, 33 years old, in mid-August 1989 no special incentives appear excessive menses, bleeding gums, with irregular fever, on September 16 to our hospital for medical treatment. Check WBC0.35 × 10 ~ 9 / L, Hb55g / L, BPC42 × 10 ~ 9 / L. Physical examination: T36 ℃, anemia appearance, systemic superficial lymph nodes is not enlarged, no yellowish skin and mucous membrane bleeding, blepharophimosis pale, breath sounds clear lungs, abdomen soft, liver and spleen not yet. Bone marrow: obvious hyperplasia, granule: red = 8.5: 1 Fine granular promyelocytic cells 64% visible Auer’s body, Pox strong positive, α-acetate palmitate (+), sodium fluoride inhibition test ( -) diagnosed as APL. On the third day of admission, begin taking RASO / mg day. On the third day of RA treatment, scattered bleed spots and purpura appeared on the skin and mucous membranes of the whole body