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本文报道垂体生长激素腺瘤126冽,均有肢端肥大症或巨人症的表现。有视力损害者15例。进行血生长激素测定者57例,其基础水平在11~80μg/L。全组均进行了X线及CT检查。除4例因鞍上瘤块过大而采用额下入路外,其余122例均采用经蝶窦入路显微手术切涂肿瘤,全组无死亡。术后发生脑脊液漏及瘤床出血各2例,施行了再次手术。术后尿崩症35例,短期内自愈。随访3个月至6年3个月。有3例因肿瘤复发而再次手术。本文对这种垂体瘤的诊断与治疗进行了讨论。
This article reports pituitary growth hormone adenomas of 126 冽, both with acromegaly or gigantism. There are 15 cases of visual impairment. Fifty-seven cases of blood growth hormone tests were performed, and their basic level was 11 to 80 μg/L. All groups were examined by X-ray and CT. Except for 4 patients who underwent subfrontal approach because of suprasellar masses, the remaining 122 patients were treated with transsphenoidal approach microsurgery and the entire group had no death. Two cases of cerebrospinal fluid leakage and tumor bed hemorrhage occurred postoperatively and reoperation was performed. There were 35 cases of diabetes insipidus after operation and self-healing in the short term. Follow-up from 3 months to 6 years and 3 months. Three patients had reoperation due to tumor recurrence. This article discusses the diagnosis and treatment of this pituitary tumor.